The use of a light probe for assessing the homogeneity of powder mixtures
โ Scribed by M.D. Ashton; C. Schofield; F.H.H. Valentin
- Publisher
- Elsevier Science
- Year
- 1966
- Tongue
- English
- Weight
- 548 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0009-2509
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In-process testing requirements for adequacy of mixing are established in 21 CFR 211.110(a)(3). Considering also, the U.S. Food and Drug Administration's draft guidance published in 1999 (Guidance for Industry, ANDAs: Blend Uniformity Analysis; http://www.fda.gov/cder/guidance/index.htm), the import
Scheme 1. Synthesis of the key fluorinated intermediate 8. Reagents and conditions: a) BnBr, NaH; b) 1. Mg, 2. CF 3 CO 2 Et; c) NaH, CS 2 , CH 3 I, THF; d) H 3 PO 2 , TEA, AIBN, dioxane, reflux; e) H 2 /Pd(OH) 2 , EtOAc; f) PPh 3 , CBr 4 , CH 2 Cl 2 .