## Abstract Dynamic nuclear polarization can be used to increase the sensitivity of solution state ^13^C magnetic resonance spectroscopy by four orders of magnitude. We show here that [1โ^13^C]glutamate can be polarized to 28%, representing a 35,000โfold increase in its sensitivity to detection at
The use of 13C-magnetic resonance spectroscopy in metabolic research
โ Scribed by Julian Lombardi; Charles R. Graham Jr.
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 957 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0955-2863
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## Abstract [1โ^13^C]Pyruvate is a readily polarizable substrate that has been the subject of numerous magnetic resonance spectroscopy (MRS) studies of in vivo metabolism. In this work ^13^CโMRS of hyperpolarized [1โ^13^C]pyruvate was used to interrogate a metabolic pathway involved in neither aero
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