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The UmuD′ protein filament and its potential role in damage induced mutagenesis

✍ Scribed by Thomas S Peat; Ekaterina G Frank; John P McDonald; Arthur S Levine; Roger Woodgate; Wayne A Hendrickson

Book ID
114329438
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
663 KB
Volume
4
Category
Article
ISSN
0969-2126

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✍ Martín Gonzalez; Roger Woodgate 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB 👁 1 views

## Abstract Recently, the __Escherichia coli umuD__ and __umuC__ genes have been shown to encode __E. coli__'s fifth DNA polymerase, pol V (consisting of a heterotrimer of UmuD′~2~C). The main function of pol V appears to be the bypass of DNA lesions that would otherwise block replication by pols I