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The ubiquitin specific protease 4 (USP4) is a new player in the Wnt signalling pathway

โœ Scribed by Bin Zhao; Claudia Schlesiger; Maria G. Masucci; Kristina Lindsten


Book ID
114778585
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2009
Tongue
English
Weight
947 KB
Volume
13
Category
Article
ISSN
1582-1838

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Members of the Wnt family of secreted glycoproteins act as short-range signaling molecules in vertebrate embryogenesis. Previous work has shown that Wnt-4 is required for kidney development. Mice lacking functional Wnt-4 fail to form pretubular cell aggregates. Wnt-4 acts as an autoinducer of the me