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The ubiquitin pathway in Parkinson's disease

✍ Scribed by Leroy, Elisabeth; Boyer, Rebecca; Auburger, Georg; Leube, Barbara; Ulm, Gudrun; Mezey, Eva; Harta, Gyongyi; Brownstein, Michael J.; Jonnalagada, Sobhanadditya; Chernova, Tanya; Dehejia, Anindya; Lavedan, Christian; Gasser#, Thomas; Steinbach, Peter J.; Wilkinson, Keith D.; Polymeropoulos, Mihael H.

Book ID
109704417
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
255 KB
Volume
395
Category
Article
ISSN
0028-0836

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Ubiquitin–proteasome system and Parkinso
Ubiquitin–proteasome system and Parkinson's disease
✍ C. Warren Olanow; Kevin St. P. McNaught 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 546 KB

## Abstract Increasing genetic, pathological, and experimental evidence suggest that neurodegeneration in both familial and sporadic forms of Parkinson's disease (PD) may be related to a defect in the capacity of the ubiquitin–proteasome system (UPS) to clear unwanted proteins, resulting in protein