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The Tyrosine Residue at 1250 of the Insulin-like Growth Factor I Receptor Is Required for Ligand-Mediated Internalization

✍ Scribed by Masahiko Miura; Renato Baserga


Book ID
115580993
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
101 KB
Volume
239
Category
Article
ISSN
0006-291X

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Insulin-like growth factor I receptor is
✍ Tiziana Deangelis; Andres Ferber; Renato Baserga πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 971 KB

## Abstract R^βˆ’^ cells are 3T3‐like cells derived from mouse embryos in which the insulin‐like growth factor I (IGF‐I) receptor (IGF‐IR) genes have been disrupted by targeted homologous recombination. These cells cannot grow in serum‐free medium supplemented by the growth factors that sustain the g