The tyrosine kinase c-Src is required for 1,25(OH)2-vitamin D3 signalling to the nucleus in muscle cells
β Scribed by Claudia Buitrago; Ricardo Boland; Ana Russo de Boland
- Book ID
- 114150134
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 370 KB
- Volume
- 1541
- Category
- Article
- ISSN
- 0167-4889
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π SIMILAR VOLUMES
1,25-dihydroxy-vitamin D(3) (1,25(OH)(2)D(3)), the hormonally active form of vitamin D(3), acts through two different mechanisms. In addition to regulating gene expression via the specific intracellular vitamin D receptor (VDR), 1,25(OH)(2)D(3) induces rapid, non-transcriptional responses involving
## Abstract In chick skeletal muscle cell primary cultures, we previously demonstrated that 1Ξ±,25(OH)~2~βvitamin D~3~ [1Ξ±,25(OH)~2~D~3~], the hormonally active form of vitamin D, increases the phosphorylation and activity of the extracellular signalβregulated mitogenβactivated protein (MAP) kinase