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The tyrosinase-positive oculocutaneous albinism locus is not linked to the β-globin locus in man

✍ Scribed by R. A. Heim; D. S. Dunn; S. E. Candy; E. Zwane; J. G. R. Kromberg; T. Jenkins

Publisher
Springer
Year
1988
Tongue
English
Weight
96 KB
Volume
79
Category
Article
ISSN
0340-6717

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✦ Synopsis

Twenty informative families have been studied. and linkage between the tyrosinase-positive oculocutaneous albinism locus and the beta-globin locus has been excluded with a maximum lod score of -9.85 at 0 = 0.05. In lower mammals there is linkage between the p locus (considered to be equivalent to the human tyrosinase-positive oculocutaneous albinism) and the beta-globin locus.

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The locus for apolipoprotein CII is clos
The locus for apolipoprotein CII is closely linked to the apolipoprotein E locus on chromosome 19 in man
✍ Ola Myklebost; Sissel Rogne; Bjørnar Olaisen; Tobias Gedde-Dahl; Hans Prydz 📂 Article 📅 1984 🏛 Springer 🌐 English ⚖ 362 KB

We have demonstrated close linkage between the genes for apolipoprotein E (apoE) and apolipoprotein CII (apoCII). Families segregating for apoE protein variants were screened for a DNA restriction fragment length polymorphism close to the apoCII gene by using an apoCII cDNA clone. The maximum lod sc