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The type II ‘decoy’ receptor: A novel regulatory pathway for interleukin 1

✍ Scribed by Francesco Colotta; Steven K. Dower; John E. Sims; Alberto Mantovani


Book ID
103584216
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
650 KB
Volume
15
Category
Article
ISSN
0167-5699

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## Abstract Endothelial cells (EC) are very responsive to the proinflammatory cytokine inter‐leukin‐1 (IL‐1). EC are induced by IL‐1 to secrete chemotactic factors and to increase expression of cell surface adhesion molecules leading to increased leukocyte adhesion. Activated EC turther contribute