Maturity onset diabetes of the young (MODY) is a genetically heterogeneous form of type 2 diabetes that is characterized by autosomal dominant inheritance, onset in early adulthood and a primary defect in insulin secretion. Mutations in at least six genes have been shown to underlie MODY, including
The Type and the Position of HNF1A Mutation Modulate Age at Diagnosis of Diabetes in Patients with Maturity-Onset Diabetes of the Young (MODY)-3
β Scribed by Bellanne-Chantelot, C.; Carette, C.; Riveline, J.-P.; Valero, R.; Gautier, J.-F.; Larger, E.; Reznik, Y.; Ducluzeau, P.-H.; Sola, A.; Hartemann-Heurtier, A.; Lecomte, P.; Chaillous, L.; Laloi-Michelin, M.; Wilhem, J.-M.; Cuny, P.; Duron, F.; Guerci, B.; Jeandidier, N.; Mosnier-Pudar, H.; Assayag, M.; Dubois-Laforgue, D.; Velho, G.; Timsit, J.
- Book ID
- 121341436
- Publisher
- American Diabetes Association
- Year
- 2007
- Tongue
- English
- Weight
- 119 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0012-1797
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Maturity-onset diabetes of the young is a genetically heterogenous autosomal dominant form of diabetes mellitus, characterized by an early age at onset and a primary defect in beta-cell function. Forty families with a clinical presentation suggestive of MODY were screened for the most common MODY su