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The tumor microenvironment: a potential arbitrator of the tumor suppressive and promoting actions of TGFβ

✍ Scribed by Carlos L. Arteaga


Book ID
114428808
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
116 KB
Volume
70
Category
Article
ISSN
0301-4681

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A delicate balance: TGF-β and the tumor
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## Abstract The activated form of TGF‐β is a known regulator of epithelial cell autonomous tumor initiation, progression, and metastasis. Recent studies have also indicated that TGF‐β mediates interactions between cancer cells and their local tumor microenvironment. Specifically, the loss of TGF‐β