The treatment of brain stem and thalamic gliomas with 78 Gy of hyperfractionated radiation therapy
โ Scribed by Michael D. Prados; William M. Wara; Michael S.B. Edwards; David A. Larson; Kathleen Lamborn; Victor A. Levin
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 788 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0360-3016
No coin nor oath required. For personal study only.
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## BACKGROUND. Prognosis for the majority of children with brain stem gliomas is dismal. In previous studies, recombinant beta-interferon (@IF) has been shown to be effective for children with recurrent brain stem gliomas and may also act synergistically with radiotherapy (RT). ## METHODS. Thir
Between May 1986 and February 1988, 57 patients were accrued to the second dose level of a Phase I/II Pediatric Oncology Group (POG) study exploring the use of hyperfractionated radiation therapy (HRT) in children with high-risk brain stem tumors. Local fields were treated with fraction sizes of 117