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The transition in frequency of Y-chromatin in males during early infancy

โœ Scribed by E. Lyberatou-Moraitou; G. S. Kourounis; P. Grigori-Kostaraki; C. Lyberatos; D. Aravantinos; D. Kaskarelis

Book ID
119839200
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
167 KB
Volume
20
Category
Article
ISSN
0009-9163

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The transition in frequency of Y chromat
The transition in frequency of Y chromatin in males during the neonatal period
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The frequency of Y chromatin, visualized as fluorescent bodies in cell nuclei from lymphocytes in blood smears, was significantly less in newborn males than in three-month-old male infants and adults. The frequency of Y chromatin-positive cells on day 0 was 36.16 +/- 9.11% and then increased daily.

Y-chromatin positive cells in the smear
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An ambisexual male infant showed a normal female karyotype by the leukocyte culture technique in two different occasions. Cultured fibroblasts from the right gonad had also a 46, XX complement. They were Y-chromatin negative. To our surprise, Y-chromatin was observed in 96% of the nuclei in smears f