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Y-chromatin positive cells in the smear preparations of the gonad from an XX male

✍ Scribed by K. Iinuma; T. Ohzeki; K. Ohtaguro; E. Higashihara; A. Tanae; Y. Nakagome


Publisher
Springer
Year
1975
Tongue
English
Weight
696 KB
Volume
30
Category
Article
ISSN
0340-6717

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✦ Synopsis


An ambisexual male infant showed a normal female karyotype by the leukocyte culture technique in two different occasions. Cultured fibroblasts from the right gonad had also a 46, XX complement. They were Y-chromatin negative. To our surprise, Y-chromatin was observed in 96% of the nuclei in smears from the uncultured gonad. It is emphasized that the examination of the uncultured gonad by the quinacrine technique is mandatory in the study of "XX males".