The transglutaminase 2 gene is aberrantly hypermethylated in glioma
β Scribed by Lisa M. Dyer; Kevin P. Schooler; Lingbao Ai; Corinne Klop; Jingxin Qiu; Keith D. Robertson; Kevin D. Brown
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 569 KB
- Volume
- 101
- Category
- Article
- ISSN
- 0167-594X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We have tested the hypothesis that H-ras transformed cells contain alterations in signal pathways important in controlling the expression of ornithine decarboxylase (ODC), the highly regulated rate-limiting activity in the biosynthesis of poly-
Transglutaminase 2 (TG2 or TGM2) is a multi-functional enzyme which catalyzes transamidation reactions or acts as a G-protein in intracellular signalling. Tgm2 -/-Mice lacking TG2 activity are glucose intolerant and show impairment of insulin secretion, suggesting an important physiological role for
## Abstract The use of molecular markers in the diagnostics of gliomas aids histopathological diagnosis and allows their further classification into clinically significant subgroups. The aim of this study was to characterize the methylation pattern of the O^6^βmethylguanineβDNA methyltransferase (_