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The Transformation Suppressor Pdcd4 Is a Novel Eukaryotic Translation Initiation Factor 4A Binding Protein That Inhibits Translation

✍ Scribed by Yang, H.-S.; Jansen, A. P.; Komar, A. A.; Zheng, X.; Merrick, W. C.; Costes, S.; Lockett, S. J.; Sonenberg, N.; Colburn, N. H.


Book ID
125494013
Publisher
American Society for Microbiology
Year
2003
Tongue
English
Weight
777 KB
Volume
23
Category
Article
ISSN
0270-7306

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## Abstract A gene coding for a protein homologous to a translation initiation factor of eukaryotes, eIF5A, was cloned from __Methanococcus jannaschii__, a hyperthermophile with an optimum growth temperature of 85 Β°C. The protein was overexpressed, purified and crystallized. The crystals were obtai