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The Transcriptional Corepressor NAB2 Blocks Egr-1-Mediated Growth Factor Activation and Angiogenesis

โœ Scribed by Parul Houston; Callum J. Campbell; John Svaren; Jeffrey Milbrandt; Martin Braddock


Book ID
115587886
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
86 KB
Volume
283
Category
Article
ISSN
0006-291X

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Binding of fibroblast growth factors (FGFs) to receptor tyrosine kinases (FGFRs) and signaling is facilitated by binding of FGF to heparan sulfate proteoglycans (HSPGs). There are multiple families of HSPGs, including extracellular and cell surface forms. An important and potentially controversial q