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The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses

✍ Scribed by Bell, Bryan D; Kitajima, Masayuki; Larson, Ryan P; Stoklasek, Thomas A; Dang, Kristen; Sakamoto, Kazuhito; Wagner, Kay-Uwe; Reizis, Boris; Hennighausen, Lothar; Ziegler, Steven F


Book ID
120059289
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
911 KB
Volume
14
Category
Article
ISSN
1529-2908

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## Abstract We have addressed the hypothesis that Notch ligands play a decisive role in determining the ability of antigen‐presenting cells to influence T cell polarization. Dendritic cells displayed distinct expression profiles of Delta and Jagged ligands for Notch when exposed to biologically rel