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The transcription factor Sox2 is required for osteoblast self-renewal

โœ Scribed by Basu-Roy, U; Ambrosetti, D; Favaro, R; Nicolis, S K; Mansukhani, A; Basilico, C


Book ID
109842428
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
740 KB
Volume
17
Category
Article
ISSN
1350-9047

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Cdk1 is required for the self-renewal of
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## Abstract Cyclinโ€dependent kinase 1 (Cdk1) is indispensible for the early development of the embryo. However, its role in maintaining the undifferentiated state of the embryonic stem (ES) cells remains unknown. In this study, we dissected the function of Cdk1 in mouse ES cells by RNAโ€interference