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Sox2 Is Required For The Self-renewal Of The Osteoblast Lineage

✍ Scribed by Alka Mansukhani; Upal Basu Roy; Silvia Nicolis; Claudio Basilico

Book ID
116322814
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
54 KB
Volume
46
Category
Article
ISSN
8756-3282

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## Abstract Cyclin‐dependent kinase 1 (Cdk1) is indispensible for the early development of the embryo. However, its role in maintaining the undifferentiated state of the embryonic stem (ES) cells remains unknown. In this study, we dissected the function of Cdk1 in mouse ES cells by RNA‐interference