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The transcription factor CCAAT/enhancer binding protein beta (C/EBPbeta) and giant cell tumors

✍ Scribed by J.J. Smink; P.U. Tunn; A. Leutz


Book ID
116323167
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
74 KB
Volume
47
Category
Article
ISSN
8756-3282

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## Abstract Giant cell tumor (GCT) of bone is an aggressive non‐cancerous tumor, which consists of multi‐nucleated osteoclast‐like giant cells, stromal cells, and monocytes. It is believed that stromal cells are the neoplastic component of this tumor. Expression of the receptor activator of nuclear