๐”– Bobbio Scriptorium
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The Total Synthesis of Ipalbidine and Ipalbine

โœ Scribed by A. E. Wick; P. A. Bartlett; D. Dolphin


Publisher
John Wiley and Sons
Year
1971
Tongue
German
Weight
686 KB
Volume
54
Category
Article
ISSN
0018-019X

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โœฆ Synopsis


Zusammenfussung. Eine Totalsynthese des Hexahydroindolizin-Alkaloids Ipalbidin (7) und seines P-D-Glucosids Ipalbin (1) wird beschricben. Dcr zentrale Syntheseschritt besteht aus ciner N-Acylierung des vinylogen Amidsystems 3, gefolgt von einer internen Kondensation zum penta-' I Upon completion of this manuscript, a synthesis of racemic ipalbidinc was reported [Z].


๐Ÿ“œ SIMILAR VOLUMES


General methods of alkaloid synthesis. X
โœ Robert V. Stevens; Yuhshi Luh ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 178 KB

## Recently, we reported' the total synthesis of (*)-isoretronecanol (1) and (+)-8-coniceine (2). A key step in each of these syntheses utilized the acid-catalyzed rearrangement of a cyclopropylimine to generate the 3-phenylthio-2-pyrroline synthon (2). The latter intermediate serves as a relative