The total synthesis of favelanone
β Scribed by Wendy Ng; Dieter Wege
- Book ID
- 104255770
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 110 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
+_)-Favelanone (1) has been synthesised by a sequence involving as the key step the cycloaddition of 6-methoxy-5-methyl-3-trimethylsilyloxyisobenzofuran-l-carbonitrile (3) to 7-bromo-5, 5-dimethylbicyclo[ 4.1. O]hept-l ( 7)-ene (4).
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The red pigment, radermachol(1). has been synthesized from 1,4-dimethoxynaphthelene In thrrfeen steps. Radermachol (l),' a red prgment Isolated from Radermachera xylocarpa, has a fused aromatlc structure not encountered previously in any other natural product A retrosynthebc analysis (Scheme 1) ind