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The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces mitochondrial and nuclear DNA damage in Caenorhabditis elegans

✍ Scribed by Bodhicharla, Rakesh; Ryde, Ian T.; Prasad, G.L.; Meyer, Joel N.


Book ID
121192640
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
368 KB
Volume
55
Category
Article
ISSN
0893-6692

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## Abstract Urinary metabolites of the tobacco‐specific nitrosamine 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK), 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol (NNAL) and its glucuronides, termed total NNAL, have recently been shown to be good predictors of lung cancer risk, years before di