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Oxidative DNA damage in tissues of pregnant female mice and fetuses caused by the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

✍ Scribed by Marek A Sipowicz; Shantu Amin; Dhimant Desai; Kazimierz S Kasprzak; Lucy M Anderson


Book ID
117468529
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
63 KB
Volume
117
Category
Article
ISSN
0304-3835

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## Abstract Urinary metabolites of the tobacco‐specific nitrosamine 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK), 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol (NNAL) and its glucuronides, termed total NNAL, have recently been shown to be good predictors of lung cancer risk, years before di