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The TITAN trial – Assessing the efficacy and safety of an anti-von Willebrand factor Nanobody in patients with acquired thrombotic thrombocytopenic purpura

✍ Scribed by Josefin-Beate Holz


Book ID
116929172
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
354 KB
Volume
46
Category
Article
ISSN
1473-0502

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## Abstract Decreased von Willebrand factor (VWF)‐cleaving protease activity (<5%) has been implicated in patients with congenital thrombotic thrombocytopenic purpura–hemolytic uremic syndrome (Upshaw‐Schulman syndrome) and associated with mutations within the __ADAMTS13__ gene. In this report, we