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The tissue distribution of tumor necrosis factor-α in rats: A compartmental model

✍ Scribed by Mary Keith; Kenneth H. Norwich; Willy Wong; Khursheed N. Jeejeebhoy


Book ID
117828218
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
114 KB
Volume
49
Category
Article
ISSN
1532-8600

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The blood residence half-life and organ distribution of recombinant human tumor necrosis factor-alpha (TNF-alpha) encapsulated in sterically stabilized liposomes, were investigated in rats bearing a soft tissue sarcoma in the hind leg. We studied the decay in blood concentration of "empty" liposomes