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The Tightness Contribution to the Brønsted α for Hydride Transfer between NAD + Analogues

✍ Scribed by Lee, In-Sook Han; Chow, Kim-Hung; Kreevoy, Maurice M.


Book ID
126931659
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
86 KB
Volume
124
Category
Article
ISSN
0002-7863

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A new mechanistic model for hydride tran
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## Abstract A mechanistic study of hydride transfer based on (simplified) NADH/NAD^+^ model systems is given. The new model originates from a classical mechanism generally indicated as being an intramolecular nucleophilic displacement reaction. There is some controversy with the results of quantum‐