The IL-2 receptor Ξ² chain gene (Il-2rb)
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Thomas R. Malek; Vladimir Vincek; Biljana Gatalica; Maja Bucan
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Article
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1993
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Springer-Verlag
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English
β 246 KB
A functional high-affinity IL-2 receptor (IL-2R) is comprised of at least three subunits (cz, [3, and 7) that cooperatively act to bind IL-2, leading to the growth of antigen-activated T lymphocytes (Hatakeyama et al. 1989;Takeshita et al. 1992). Mouse and human IL-2Rc~ chain genes (I1-2ra) have bee