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The therapeutic potential of endothelin receptor antagonists in cardiovascular disease

✍ Scribed by Matthias Barton; Wolfgang Kiowski

Book ID
107541013
Publisher
Springer
Year
2001
Tongue
English
Weight
819 KB
Volume
3
Category
Article
ISSN
1522-6417

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## Abstract The chemokine receptor CXCR4 possesses multiple critical functions in normal and pathologic physiology. CXCR4 is a G‐protein‐coupled receptor that transduces signals of its endogenous ligand, the chemokine CXCL12 (stromal cell‐derived factor‐1, SDF‐1). The interaction between CXCL12 and