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The telomeric part of the HLA region predisposes to rheumatoid arthritis independently of the class II loci

✍ Scribed by Eric Zanelli; Gavin Jones; Maria Pascual; Peter Eerligh; Arno R. van der Slik; Aeilko H. Zwinderman; Willem Verduyn; Geziena M.T. Schreuder; Edwin Roovers; Ferdinand C. Breedveld; René R.P. de Vries; Javier Martin; Marius J. Giphart

Book ID: 117414603
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 267 KB
Volume: 62
Category: Article
ISSN: 0198-8859
DOI: 10.1016/s0198-8859(00)00227-5

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## Objective: To evaluate the contributions of hla-dq and -dr polymorphisms to susceptibility to rheumatoid arthritis (ra) in a population in southern spain, and to compare the value of the shared epitope (se) and ra protection (rap) models in accounting for the hla class ii region's contribution t