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The Synthesis of Tryptophan Peptides

✍ Scribed by Wilchek, M.; Patchornik, A.


Book ID
126165765
Publisher
American Chemical Society
Year
1963
Tongue
English
Weight
275 KB
Volume
28
Category
Article
ISSN
0022-3263

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## Abstract A modified tryptophan, β‐[2‐(2,2,5,7,8‐pentamethylchroman‐6‐sulphonyl)‐indol‐3‐yl]alanine, Trp(2 βˆ’ Pmc) = Tpc has been synthesized. Replacement of tryptophan in a bovine lactoferricin model peptide with the modified tryptophan resulted in peptides with a substantially increased antibact