Synthesis of methyl 1-(3,4-dichlorobenzy
โ
Thomas J. Schwan; Joseph E. Gray; George C. Wright
๐
Article
๐
1979
๐
John Wiley and Sons
๐
English
โ 208 KB
Methyl 1-(3,4-dichlorobenzyl)-hexahydro-2,3-dioxo-4-pyridinecarboxylate was prepared by alkylation of methyl hexahydro-2,3-dioxo-4-pyridinecarboxylate with alpha,3,4-trichlorotoluene. The compound showed significant antifungal activity when challenged by a spectrum of pathogenic yeast species in a m