A facile synthesis of symmetrical 1,1-di
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Gerald L. Larson; David HernΓ‘ndez
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Article
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1982
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Elsevier Science
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French
β 201 KB
The reaction of ethyl trimethylsilylacetate with two equivalents of a Grignard reagent in ether followed by treatment with acid gives 1,1-disubstituted ethylenes in excellent yield. The use ofghydroxysilanes in the formation of olefins has been a useful reaction in organic chemistry since the first