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An efficient synthesis of symmetrical 2,5-diaryl-1,3,4-oxadiazoles

✍ Scribed by Sergei I. Luiksaar; Leonid I. Belen’kii; Mikhail M. Krayushkin

Book ID
111730093
Publisher
Royal Society of Chemistry
Year
1998
Tongue
English
Weight
44 KB
Volume
8
Category
Article
ISSN
0959-9436

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## Abstract Several new 2,5‐disubstituted 1,3,4‐oxadiazoles have been synthesized in good yields by reaction of aromatic acids with hydrazine dihydrochloride in a mixture of orthophosphoric acid, phosphorus pentoxide and, in general, with addition of phosphorus oxychloride to the reaction mixture.