Transformations in the Isoxazole Series:
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Alfons Pascual
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Article
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1991
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John Wiley and Sons
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German
β 790 KB
Substitued N-(isoxazol-4-yl)thioureas 1 undergo a transformation in the presence of hexacarbonylmolybdenum and acid to yield functionalized thiazoles 3 in a one-pot reaction. In a few cases, 1,4,5-trisubstituted dihydroimidazoleth,iones 4 are also isolated as side products. Mechanistic consideration