One-step synthesis of 2,4,5-trisubstitut
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Chuang-Jun Zhang; Wen-Yong Han; Mi-Xiang Gao; Fei-Fei Xu; Zun-Ting Zhang
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Article
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2011
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Journal of Heterocyclic Chemistry
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English
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## Abstract A simple and straightforward methodology towards the synthesis of 2,4,5โtrisubstituted pyrimidines has been developed by oneโstep reaction of isoflavones with thiourea or guanidine. Ten 2โmercaptoโ4,5โdiphenylpyrimidines and eight 2โaminoโ4,5โdiphenylpyrimidines were reported. All of th