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The synthesis of reduced metabolites of aldosterone by subcellular fractions of rat kidney: Effects of antimineralocorticoids

✍ Scribed by Martin J. McDermott; Mary Freiberger; Syed A. Latif; David J. Morris

Book ID
116005131
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
860 KB
Volume
23
Category
Article
ISSN
0022-4731

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Inorganic mercury, administered to rats in a single dose of 0.5 mg Hg/kg is accumulated in the kidneys mainly in the soluble (54%) and nuclear (30%) fractions, showing decreasing tendency with time. Mitochondrial and microsomal fractions, initially accumulating approx. 11 and 6% of total Hg, show a