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The synthesis of potentially selective inhibitors of dihydroorotate dehydrogenase. The utilization of chemoselective Suzuki cross-coupling reactions in a parallel synthesis

✍ Scribed by Amanda E Sutton; Jon Clardy

Book ID
104211568
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
101 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

A series of potentially selective inhibitors of dihydroorotate dehydrogenase (DHODH) were synthesized via iterative, chemoselective Suzuki cross-couplings utilizing biaryl chlorides as key intermediates.

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