The synthesis of optically active isopropyl methylphosphonofluoridate (Sarin): (Preliminary communication)
โ Scribed by H. L. Boter; A. J. J. Ooms; G. R. van Den Berg; Miss C. van Dijk
- Book ID
- 104587158
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 216 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0165-0513
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๐ SIMILAR VOLUMES
## Abstract The conjugate addition of the chiral, nonโracemic alkoxyโenolates **5** and **6** to nitroolefins furnishes the hydroxynitroesters **7โ13**, which are catalytically hydrogenated to give the lactams **14โ18**. The configuration of adduct **7** from nitroethylene was elucidated by NMR. an
The synthesis of the cyclophane-type molecular dyads 1 and 1 . Zn was accomplished by Bingel macrocyclization of porphyrin-tethered bis-malonates 5 or 5 . Zn, respectively, with C 60 ( Scheme). In these macrocycles, the doubly bridged porphyrin adopts a close, tangential orientation relative to the