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The synthesis of opiorphin and studies on its binding ability toward Cu(II)

✍ Scribed by Aleksandra Kotynia; Elżbieta Kamasz; Hanna Czapor; Justyna Brasuń

Book ID: 104097588
Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 238 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2010.02.172

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✦ Synopsis

Opiorphin (OPI) is an endogenous pentapeptide isolated from human saliva. A characteristic feature of this peptide is the presence of an N-terminal Gln residue. The synthesis and binding abilities of opiorphin toward Cu(II) ions are described. The use of potentiometric and spectroscopic methods allows us to propose the binding mode of the formed complexes.

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