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The synthesis of novel tetradentate ligands derived from salen and their application in enantioselective silylcyanation of aldehydes

โœ Scribed by Chengwei Lv; Mei Wu; Shoufeng Wang; Chungu Xia; Wei Sun


Book ID
108284602
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
1010 KB
Volume
21
Category
Article
ISSN
0957-4166

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A novel procedure for selective direct N,N-alkylation of the chiral Betti base was developed, and a new family of chiral ligands, (S)-1-(a-cycloaminobenzyl)-2-naphthols, were prepared. The ligands with five-and six-membered cyclic amines showed highly efficient asymmetric induction in the addition o