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The synthesis of novel amino acids via hydroboration-Suzuki cross coupling

✍ Scribed by Andrew D. Campbell; Tony M. Raynham; Richard J.K. Taylor

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
212 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

The Garner aldehyde-derived methylene alkene has been hydroborated using 9-BBN and the resulting organoborane employed in palladiurn-catalysed Suzuki coupling reactions to produce, offer hydrolysis-oxidation, a range of novel amino acids as their N-BOC protected derivatives.

📜 SIMILAR VOLUMES

The direct synthesis of novel enantiomer
The direct synthesis of novel enantiomerically pure α-amino acids in protected form via Suzuki cross-coupling
✍ Philip N Collier; Andrew D Campbell; Ian Patel; Richard J.K Taylor 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 215 KB

Protected allylglycine has been hydroborated and the intermediate organoborane employed in Suzuki coupling reactions with a number of ole®nic, aromatic and heteroaromatic bromides and iodides to produce a range of novel a-amino acids in good, unoptimised yields.

ChemInform Abstract: Synthesis of Unnatu
ChemInform Abstract: Synthesis of Unnatural Amino Acids via Suzuki Cross-Coupling of Enantiopure Vinyloxazolidine Derivatives.
✍ Mark Sabat; Carl R. Johnson 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 39 KB 👁 1 views

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