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The Synthesis of New C2-Symmetric Chiral 1,4-Diamino Motif and Application in Catalytic Asymmetric Alkynylation of meso-Epoxides.

✍ Scribed by Chengjian Zhu; Minghua Yang; Jiangtao Sun; Yuhua Zhu; Yi Pan


Publisher
John Wiley and Sons
Year
2004
Weight
96 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract A new __C__~2~‐symmetric chiral catalyst 3,5‐bis[(2__S__)‐(hydroxy‐diphenylmethyl)‐ pyrrolidin‐1‐ylmethyl]‐1,3,4‐oxadiazole was successfully synthesized by the reaction of 2,5‐dichloromethyl‐1,3,4‐oxadiazole with (__S__)‐α,α‐diphenyl‐2‐pyrrolidinemethanol, and applied to the catalytic a