𝔖 Bobbio Scriptorium
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The synthesis of N-deuteromethylated desipramine and imipramine

✍ Scribed by G. J. Shaw; S. P. Markey


Book ID
102369957
Publisher
John Wiley and Sons
Year
1977
Tongue
French
Weight
271 KB
Volume
13
Category
Article
ISSN
0022-2135

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✦ Synopsis


)have been synthesised f o r use as i n t e r n a l standards i n mass spectrometric determinations. compounds i s reported.


πŸ“œ SIMILAR VOLUMES


Synthesis of tritium-labelled imipramine
✍ L. A. Yakovleva; Ju. L. Kaminski; L. P. Sosnova; B. K. Kudelin πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 French βš– 189 KB

## Abstract [G‐^3^H]imipramine and [G‐^3^H]desipramine with specific activities 110–160 and 80–100 kCi/mol, respectively were synthesized by high temperature solid‐phase catalytic isotope exchange with gaseous tritium.

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The influence of orally administered activated charcoal on organ concentrations of parenteral imipramine and desipramine was investigated. Ancillary distribution experiments indicated that the gastroenteral cycle of these substances might be more important than the enterohepatic cycle. Nevertheless