The Synthesis of Isothiocyanates from Amines
β Scribed by HODGKINS, JOE E.; ETTLINGER, MARTIN G.
- Book ID
- 111872694
- Publisher
- American Chemical Society
- Year
- 1956
- Tongue
- English
- Weight
- 251 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
Single ci-ystals of 2a were obtained from n-pentane at -78 'C. C,,H,,N,Nb, M , = 400.41. yellow block (0.51 x 0.43 x 0.38 mm). triclinic. space group Pi (no. 7). 0=885.9(1), h=1065.5(1), r.=1276.7(1)pm. 2=70.47(1). p = X549(1).;. =70.58(1) . V=10704(2)x10' p m 3 . 2 = 2.pCaiib =1.242gcm-',
Alkyl and aryl amines are converted smoothly to the corresponding isothiocyanates via the dithiocarbamates in good to excellent yields using di-tert-butyl dicarbonate (Boc 2 O) and 1-3 mol % of DMAP or DABCO as catalyst. As most of the byproducts are volatile, the work-up involves simple evaporation