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The Synthesis of Glycyl-L-prolylglycyl and Glycyl-L-prolyl-L-alanyl Oligopeptides and Sequential Polypeptides 1

✍ Scribed by Bloom, S. M.; Dasgupta, S. K.; Patel, R. P.; Blout, E. R.

Book ID
126868934
Publisher
American Chemical Society
Year
1966
Tongue
English
Weight
949 KB
Volume
88
Category
Article
ISSN
0002-7863

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The related tripeptides glycyl-l-prolyl-l-glutamic acid (GPE) and glycyl-l-2methylprolyl-l-glutamic acid (G-2-MePE) were labelled with commercially available [1,2,3,4,5-13 C 5 , 2-15 N 1 ]-l-glutamic acid in 3 steps in excellent overall yield with high isotope incorporation. A related cyclic dipepti