✦ LIBER ✦

The synthesis of [fluorophenyl-3H(N)] ocfentanil and [fluorophenyl-3H(N)] brifentanil

✍ Scribed by C. N. Filer; R. P. Nugent; B. S. Huang

Publisher: John Wiley and Sons
Year: 1995
Tongue: French
Weight: 334 KB
Volume: 36
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580361102

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✦ Synopsis

Abstract

[Fluorophenyl‐^3^H(N)] Ocfentanil (1b) and [fluorophenyl‐^3^H(N)] brifentanil [2b] were synthesized by catalytic tritiation of appropriate bromo precursors (1a, 2a). The products were purifled by preparative HPLC and characterized chromatographically and by proton decoupled ^3^H NMR.

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