Halide-assisted glycosyIation, using a non-p~icipating Z-substituent (benzyl) in the glycosyl halide, was used to obtain the ~-D-gaiactosyl linkage and silver triflate promotion with a participating 2-substituent (benzoyl) was used to obtain the /3-D-galactosyl linkage in a facile synthesis of the t
The synthesis of derivatives of O-β-d-galactopyranosyl-(1→3)-O-(2-acetamido-2-deoxy-α-d-galactopyranosyl)-l-serine and -l-threonine
✍ Scribed by Vicente Verez Bencomo; Jean-Claude Jacquinet; Pierre Sinaÿ
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 229 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0008-6215
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📜 SIMILAR VOLUMES
In a continuing program for the synthesis of oligosaccharides that occur as part of mutinous glycoconjugates, we previously described\* the synthesis of the disaccharide methyl 3-0-(2-acetamido-2-deoxy-P-D-glucopyranosyl)-a-D-galactopyranoside (1). We have also demonstrated that 1 could be readily
Condensation of benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-a-D-galactopyranoside with 2,3,4-tri-o-acetyl-a-D-fucopyranosyl bromide in 1: 1 nitromethane-benzene, in the presence of powdered mercuric cyanide, afforded benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-0-(2,3,4-tri-O-acetyl-P-D-fucopyran