Improvements have baen made to the synthesis of 5-aminasalicylic wid (S-ASA) in order to make it applicable for the small-scale synthesis of 5-smidcerboxvl-l ~l s a l i c y l i c acid.
The Synthesis of Acetyl-1-C14-Salicylic Acid†
✍ Scribed by Clappison, Jean W. ;Hummel, J.P. ;Paul, W.D. ;Routh, J.I.
- Publisher
- Elsevier
- Year
- 1951
- Weight
- 85 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0095-9553
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📜 SIMILAR VOLUMES
Procedures for the preparation of UDP-N-[1-14C]acetyl-D-glucosamine and UDP-N-[1-14C]acetyl-D-galactosamine with very high specific activities are described. The overall yield based on the amount of [1-14C]acetate used is greater than 80%. The N-acetyl-D-glucosamine-alpha-1-phosphate used in this sy
## Abstract The title work proceeds in five steps and 16% overall yield from sodium [1‐^14^C]acetate, which was converted by bromination followed by ethoxide displacement and reaction with phthaloyl dichloride to ethoxy[1‐^14^C]acetyl chloride. The thermal[2+2]cycloaddition of tetraethoxyethene wit